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Real-Life Case Studies:
Navigating Lyme Disease Diagnosis & Care

Lyme disease is a diagnostic puzzle that challenges even the most experienced clinicians. These case studies unpacks the intricate journey of a patient navigating the labyrinth of Lyme disease—from early, subtle signs that can easily be overlooked, to the diagnostic challenges posed by co-infections and seronegative presentations.

You’ll see how staying alert to nuances in symptom patterns and employing an integrative mindset can make all the difference in identifying and managing this elusive disease.

Follow this patient’s journey as we explore key decision points, diagnostic hurdles, and treatment strategies that highlight the critical role of clinical vigilance and personalized care in overcoming this often-misunderstood illness.

Sr. No.Case Study
1Research at the Lyme Disease Center
2The Lyme Disease Expert-first undiagnosed and then properly diagnosed
3Johns Hopkins Lyme Disease Research Center
4Tulane University Case Study
5Lyme disease with seizure and pneumonia
6ScienceDirect: Lyme Disease and Heart Block
7American Journal of Case Reports
8Journal of Community Hospital Internal Medicine Perspectives
9PMC: Case Report from Pulaski County, Virginia
10Advance Research on ME/CFS, Long COVID, and Chronic Lyme Disease
11The Lyme Disease Expert: Case Study from New York
12Bilateral Facial Palsy in Lyme Disease
13Lyme Disease Presenting as Complete Heart Block
14Lyme Disease with Atypical Lesions
15Chronic Lyme Disease with Multiple Infections
16Lyme Disease and Hemi-Diaphragmatic Paralysis
17Lyme Disease Surveillance and Epidemiology in the United States
18Lyme Disease Surveillance and Data - CDC
19Novel Lyme vaccine shows promise
20Yale scientists identify protein that protects against Lyme disease
21A bacterial remnant may explain arthritis in Lyme patients
22Treating Lyme disease in 2018: advances and misconceptions
23Ancient History of Lyme Disease in North America Revealed with Bacterial Genomes
24How a tick gut gene serves as a gateway for Lyme disease
25Lyme Disease Imposes Large Cost On the Northeast United States
26Research note: Lyme bacteria mark out cell division locations for their progeny
27Lyme disease enhances spread of emerging tick infection
28Research in the News: Key to Lyme disease’s locale may be found in the gut of a tick
29Even after Lyme disease is gone, its remains may perpetuate inflammation
30Birds Play an Important Role in the Spread of Lyme Disease, Yale Study Finds
31Lyme Disease
32Other Tick-Borne Diseases
33Lyme Disease Case Map
34Patient Case Studies Lyme disease uk
35On the Trail of a Vaccine for Lyme Disease: Yale Researchers Target Tick Saliva
36Lyme Bacterium, Once Nearly Eradicated In U.S., Rebounded With Forests
37The Season of Ticks: Could Climate Change Worsen Lyme Disease?
38Interrupting the Lyme Disease Life Cycle
39tnprc.tulane.edu-Lyme Disease
40Study finds Lyme bacteria can survive antibiotic treatment months after infection
41Could long-dead bacteria be the culprit behind lingering Lyme symptoms?
42Study finds evidence of persistent Lyme infection in brain despite aggressive antibiotic therapy
43Tulane study: combined antibiotics more effective against Lyme disease
44Lyme carditis: A clinical case report
45Clinical Care of Lyme Disease
46Lyme Disease, TMD & Facial Pain – Three Case Studies
47Lyme Disease in the U.S. Originated in Europe
48Risk of Lyme Disease Very Low for Most People Bitten by a Tick, Yale Researcher Says
49Ticks Now Found to Carry a New Infectious Agent Related to the Lyme Disease Bacteria
50Long-Term Treatment Outcomes For Lyme Disease Patients Are Positive, Yale Researchers Find
51Study finds potential new treatment path for lasting Lyme disease symptoms
52Lyme researcher seeks answers from evasive disease
53Tulane researchers to develop new Lyme vaccine with lasting protection
54Tulane scientist awarded grant to develop novel Lyme therapy
55Clinical Care and Treatment of Lyme Arthritis
56Clinical Care and Treatment of Lyme Carditis
57Atypical Lyme Disease Rash: A Case Report
58Acute Lyme Disease With Atypical Features due to Borrelia mayonii
59Atypical Lyme Disease Rash: A Case Report
60A Case of Early Disseminated Neurological Lyme Disease
61Atypical presentation of Lyme disease in a returning traveler: A case report
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